Ascentis® Express C8 HPLC Columns by Merck – Enhanced Efficiency for Nonpolar Compound Separation
Laboratories face challenges separating less hydrophobic compounds or achieving faster retention when C18 columns fall short. Ascentis® Express C8 columns with Superficially Porous Silica Particles technology deliver superior speed, efficiency, and reliable results for demanding analytical applications. Explore how these columns streamline nonpolar compound analysis and meet strict industry demands.
Why Choose Ascentis® Express C8
- Higher throughput: Delivers higher speed and efficiency than fully porous particles of the same size.
- System productivity: Converts an HPLC system into a fast HPLC workhorse with maximum speed and performance.
- Reliable analytical consistency: Supports inert, stable, and reproducible operation for dependable results.
- Retention control for challenging analytes: Provides enhanced retention for less hydrophobic compounds.
- Shorter analysis time when C18 retention is excessive: Enables faster separation when retention on C18 is too long.
- Better fit for strongly retained nonpolar compounds: Addresses separations where nonpolar compounds are retained too strongly by a traditional C18 column.
- Preparative loading support: Offers suitability for preparative loading capacity.
Key Features of Ascentis® Express C8
- Particle Technology: Superficially Porous Silica Particles using Fused-Core® Technology.
- Bonded Phase Silica: Type B silica bonded phase architecture.
- Phase Chemistry: Dimethyloctyl.
- Functional Role: C8 column option for method selection when a C18 does not provide the desired separation.
Ascentis® Express C8 Technical Specifications
| Ascentis® Express C8 Specifications | |
|---|---|
| Silica: | Type B (High purity silica) |
| Particle Platform: | Superficially porous particles (SPP) |
| Phase Chemistry: | Dimethyloctyl |
| Particle Size: | 2.0 µm / 2.7 µm / 5.0 µm |
| Pore Size: | 90 Å |
| Carbon Load: | 4.8% / 5.4% / 3.7% |
| Surface Area: | 120 m²/g / 135 m²/g / 90 m²/g |
| pH Range: | 2 – 9 |
| Max Temperature at Low pH: | 60 °C |
| Max Temperature at High pH: | 40 °C |
| Endcapped: | Yes |
Application and Usage of Ascentis® Express C8
- Method adjustment when a C18 does not give the desired separation.
- Sample analysis for compounds that are difficult to retain or resolve on a C18.
- Use with nonpolar compounds that are retained too strongly by a traditional C18 column.
- Fast separation of dyes.
- Analysis of spice mixtures to determine adulteration in the context of Sudan I contamination incidents.
With more than 23 years of expertise, Chemical Express is the official distributor of Merck in Thailand. Order Ascentis® Express C8 columns and other Merck analytical products from Chemical Express to ensure access to genuine, high-performance solutions for your chromatography needs.
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