Aquastar® Water Standards from Merck: Certified Precision for Karl Fischer Reagents & Accurate Water Content Determination

Accurate water content analysis is crucial for chemical and pharmaceutical industries. Aquastar® water standards by Merck offer certified reference materials for titer determination, equipment qualification, and result verification, produced under strict ISO standards. This page guides you through their benefits and applications for analytical excellence.

Why choose Aquastar® water standards

• Reliable analytical decisions: Supports reliable and correct results for Karl Fischer titer determination, instrument monitoring, and result checks.
• Confidence in measured values: Helps verify measuring results to evaluate their accuracy and the performance of the titration process.
• Stronger quality management support: Provides a batch-specific Certificate of Analysis that is suitable for QM documentation.
• High result confidence: Offers highly precise and accurate standards for routine analytical control.
• Broad laboratory utility: Covers key needs from daily titer determination to instrument qualification and verification of measured results.

What Aquastar® water standards include

• Product classification: Aquastar® water standards are Certified Reference Materials in accordance with ISO 17034.
• Measurement and release: The standards are measured using validated procedures in a DIN EN ISO/IEC 17025 accredited laboratory.
• Quality documentation: A batch-specific certificate of analysis is provided for QM documentation.
• Available formats: The Aquastar® portfolio includes both solid and liquid water standards.
• Ampoule standards: Aquastar® water standards in ampoules are available in different concentrations.
• Ampoule composition: The ampoule standards consist of solvent mixtures with a defined water content.
• Reference testing: The ampoule standards are tested against standard reference material from NIST, National Institute of Standards and Technology, Gaithersburg, USA.
• Certificate contents for ampoules: Each package contains a batch-specific certificate with the exact measured water content of the batch, uncertainty data, measuring method, the NIST batch, and minimum shelf-life.
• Special standards: The portfolio includes a fully solid standard for the Karl Fischer oven method.
• Additional portfolio elements: Special standards also include an oil standard and a lactose standard for the pharmaceutical sector.

How Aquastar® water standards are used

• Titer determination: Aquastar® water standards are used for titer determination of volumetric Karl Fischer reagents.
• Daily titer determinations and instrument checks: Aquastar® water standards in ampoules are available in different concentrations for daily titer determinations and instrument checks.
• Monitoring and qualification of Karl Fischer instruments: The Aquastar® range includes water standards for monitoring and qualification of Karl Fischer instruments.
• Checking and verifying measuring results: These standards are used for checking measuring results and for verifying measuring results to evaluate their accuracy and the performance of the titration process.
• Use with volumetric Karl Fischer reagents: Water standard 1% is recommended for titer determination with the volumetric method using one component and two component reagents.
• Use with the coulometric method: Water standards 0.01% and 0.1% are preferred for the coulometric method.
• Verification of low water content results in volumetry: Water standards 0.01% and 0.1% are also usable to verify low water content results in volumetry.
• Karl Fischer oven method: A special Aquastar® water standard is available as an entirely solid standard for the Karl Fischer oven method.

Available Water Standards

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