Ascentis® Express AQ-C18 by Merck: Superior Stability and Retention for 100% Aqueous HPLC Applications
Achieving reliable chromatographic separation in highly-aqueous mobile phases is challenging due to phase collapse in standard C18 columns. The Ascentis® Express AQ-C18 column from Merck, featuring Fused-Core® particles and proprietary polar modification, is engineered for stable and enhanced retention of polar compounds in up to 100% aqueous environments. Explore how this solution meets demanding analytical needs.
Benefits of Ascentis® Express AQ-C18
- Reliable operation in highly aqueous mobile phases: Supports highly-aqueous mobile phases up to 100% aqueous without the risk of phase collapse.
- Resistance to de-wetting: Provides dependable use under aqueous conditions where standard C18 columns can be challenged by de-wetting.
- Improved retention for polar compounds: Delivers enhanced retention of polar compounds under 100% aqueous conditions.
- Consistent chromatographic behavior after interruption: Maintains retention and resolution after the pump is stopped and restarted under 100% aqueous conditions.
Features of Ascentis® Express AQ-C18
- Column format: U/HPLC column.
- Particle architecture: Based on Fused-Core® particles.
- Particle platform: Superficially porous particles (SPP).
- Bonded phase: C18 bonded phase.
- Preparation procedure: Prepared using a proprietary procedure incorporating a small amount of polar silane.
- Phase chemistry: Polar modified octadecyl.
- Endcapping: Endcapped.
Technical Specifications of Ascentis® Express AQ-C18
| Silica | Type B (High purity silica) |
| Particle Platform | Superficially porous particles (SPP) |
| Phase Chemistry | Polar modified Octadecyl |
| Particle Size | 2.7 μm |
| Pore Size | 90 Å |
| Carbon Load | 6.5% / 6.7% / 5.6% |
| Surface Area | 120 m²/g / 135 m²/g / 90 m²/g |
| pH Range | 2-9 |
| Max Temperature at Low pH | 60 ° |
| Max Temperature at High pH | 40 ° |
| Endcapped | Yes |
Application and Usage of Ascentis® Express AQ-C18
- Use with highly-aqueous mobile phases, including up to 100% aqueous conditions.
- Use for HPLC and UHPLC separations performed under 100% aqueous conditions.
- Use for retaining polar compounds under 100% aqueous mobile phase conditions.
Chemical Express, with over 23 years of expertise and as the official distributor of Merck in Thailand, offers the Ascentis® Express AQ-C18 and related columns. Access high-quality HPLC solutions and expert service for your analytical needs through Chemical Express.
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