Ascentis® Express C18 by Merck: High-Speed, High-Resolution HPLC/UHPLC for Precise Analytical Results
Laboratories require rapid, reliable, and high-resolution chromatographic separations to meet demanding analytical challenges. The Ascentis Express C18 HPLC column utilizes innovative Fused-Core® technology, providing unmatched speed and efficiency to elevate your chromatographic results. Discover how this advanced column addresses selectivity, reproducibility, and loading capacity needs in today’s analytical chemistry world.
Benefits of Ascentis Express C18 HPLC Column
- Faster separations: Delivers higher speed than fully porous particles of the same size for more rapid chromatographic work.
- Higher efficiency: Provides higher efficiency than fully porous particles of the same size, with column efficiency typically 40% higher than fully porous particulate columns with the same particle size.
- High-resolution results: Enables high speed and high resolution separations on HPLC and UHPLC instruments.
- Improved system performance: Can help convert an HPLC system into a faster, high-performance workhorse.
- Method flexibility: Offers broad selectivity to support analytical method development and separation optimization.
- Consistent analytical results: Supports inert, stable, and reproducible operation for dependable chromatography.
- Preparative suitability: Provides loading capacity suitable for preparative work.
Key Features of Ascentis Express C18 HPLC Column
- Column format: Fused-Core® HPLC column.
- Particle platform: Superficially porous silica particles (SPP) with Fused-Core® technology.
- Phase chemistry: Octadecyl (C18).
- Silica type: Type B silica.
- Surface treatment: Endcapped.
Technical Specifications of Ascentis® Express C18
| Specification | Technical Data |
|---|---|
| Silica | Type B (High purity silica) |
| Particle Platform | Superficially porous particles (SPP) |
| Phase Chemistry | Octadecyl |
| Particle Size | 2.0 μm / 2.7 μm / 5.0 μm |
| Pore Size | 90 Å |
| Carbon Load | 6.5% / 6.7% / 5.6% |
| Surface Area | 120 m²/g / 135 m²/g / 90 m²/g |
| pH Range | 2 -9 |
| Max Temperature at Low pH | 60 °C |
| Max Temperature at High pH | 40 °C |
| Endcapped | Yes |
Application and Usage of Ascentis® Express C18
- Primary application area: U/HPLC columns for fast and high resolution applications.
- Method development starting point: Ascentis® Express C18 is the first choice for starting a new method.
- Recommended mobile phases: Best used with mobile phases that are mixtures of methanol and water or acetonitrile and water.
- Retention guidance: Increasing the organic solvent content will typically reduce sample retention.
- Temperature guidance: Elevated temperatures at 40–60 °C reduce mobile-phase viscosity and enable faster flow rates with lower column pressure for higher sample throughput.
- Named application: UHPLC-MS analysis of cannabinoids using Ascentis® Express C18.
With over 23 years of expertise, Chemical Express is the official distributor of Merck in Thailand. The Ascentis® Express C18 and related products are available through Chemical Express, giving you access to genuine, high-performance chromatography solutions. We are committed to supporting your analytical needs with Merck products from our portfolio.
Have questions about Ascentis® Express C18 or ready to order?
Simply fill out our Inquiry Form or chat with us instantly on Line using the buttons below.
We’re here to help!
English 
Thai