ASSET™ EZ4 Dry Samplers for Isocyanates: Exceptional Sensitivity for Air Monitoring in Industrial Hygiene

Ensuring compliance with air quality regulations and occupational safety is critical across industries where isocyanates are present. ASSET™ EZ4 Dry Samplers, developed by Merck, provide an easy-to-use, highly sensitive method for comprehensive collection and measurement of vapor-phase and aerosol isocyanates, addressing common challenges in air monitoring and analytical chemistry.

Benefits of ASSET™ EZ4 Dry Samplers

• Provide exceptional sensitivity for collection and measurement of vapor-phase and particulate isocyanates.
• Easy to use and safe to wear during industrial hygiene sampling.
• ASSET™ EZ4-NCO Dry Sampler supports comprehensive monitoring by collecting the full range of isocyanate monomers and oligomers.
• ASSET™ EZ4-ICA Dry Sampler enables targeted low level sampling by collecting isocyanic acid (ICA) and methyl isocyanate (MIC).
• Workplace productivity can increase during industrial hygiene (IH) sampling because work shifts do not need to be interrupted for sampler exchange.
• Fewer sampler exchanges can reduce the number of samplers required to cover a work shift and reduce the cost of analysis.
• Reliable low detection limits are achievable at 50 to 100× below existing methods.
• The only device stated to measure both vapor phase and particulate isocyanates.
• Sampling and analysis can be streamlined with no interferences and no field extraction.
• Reduced shipping and handling charges support lower logistical overhead.
• A 2 year shelf life supports longer term stocking and readiness for planned monitoring.

Key Features of ASSET™ EZ4 Dry Samplers 

• Product type: ASSET™ EZ4 Dry Samplers for Isocyanates are designed for air monitoring and analytical sample preparation of isocyanates, enabling collection and measurement of vapor-phase and aerosol or particulate isocyanates.
• Two sampler variants: The ASSET™ EZ4 sampler family includes two formats for different analytical targets, ASSET™ EZ4-NCO Dry Sampler and ASSET™ EZ4-ICA Dry Sampler.
• ASSET™ EZ4-NCO Dry Sampler target analytes: Designed to collect the full range of isocyanate monomers and oligomers.
• ASSET™ EZ4-ICA Dry Sampler target analytes: Designed to collect isocyanic acid (ICA) and methyl isocyanate (MIC) at low levels.
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• Sampler construction: DBA impregnated glass fiber filters are housed in a denuder and filter cassette.
• Derivatization outcome: The denuder and filter cassette configuration ensures both vapor phase and aerosol or particulate isocyanates are derivatized to form stable derivatives.
• Validated sampling method: Sampling is fully validated according to ISO 17734-1:2013.
• LC-MS analytical support: The samplers are fully supported by certified reference materials for LC-MS analysis, including calibration and internal standards.

Technical Specifications for ASSET™ EZ4 Dry Samplers 

• ASSET™ EZ4-NCO Dry Sampler
  • Sampling Flow Rate: From 20 mL/min – 850 mL/min
  • Sampling Time: From 5 minutes up to 12 hrs.
  • Storage: Ambient (before and after sampling)
  • Stability: 4 weeks after sampling
• ASSET™ EZ4-ICA Dry Sampler
  • Sampling Flow Rate: From 20 mL/min – 200 mL/min
  • Sampling Time: From 5 minutes up to 4 hrs.
  • Storage: Refrigeration (before sampling); Ambient (after sampling)
  • Stability: 2 weeks after sampling

Application and Usage of ASSET™ EZ4 Dry Samplers for Isocyanates in Industrial Hygiene

• Air monitoring context: Intended for workplace air and industrial hygiene sampling where isocyanates are present, supporting collection and measurement of vapor-phase and particulate or aerosol isocyanates.
• Target analytes by sampler type: ASSET™ EZ4 NCO Dry Sampler collects the full range of isocyanate monomers and oligomers; ASSET™ EZ4 ICA Dry Sampler is designed to collect isocyanic acid (ICA) and methyl isocyanate (MIC) at low levels.
• Sampling approach: Air is drawn through the dry sampler to collect and measure both vapor-phase and particulate isocyanates, with the method designed so the collected isocyanates form stable derivatives.
• ASSET™ EZ4 NCO sampling conditions: Sampling flow rate from 20 mL/min to 850 mL/min, with sampling time from 5 minutes up to 12 hrs.
• ASSET™ EZ4 ICA sampling conditions: Sampling flow rate from 20 mL/min to 200 mL/min, with sampling time from 5 minutes up to 4 hrs.
• Storage and post sampling stability: EZ4 NCO is stored ambient before and after sampling and is stable for 4 weeks after sampling; EZ4 ICA requires refrigeration before sampling, ambient after sampling, and is stable for 2 weeks after sampling.
• Analytical method alignment: The sampling method is validated according to ISO 17734-1:2013 for determination of isocyanates in air using liquid chromatography and mass spectrometry with dibutylamine derivatives, with supporting references including ISO 17734-2:2013 and ISO/TR 17737:2007.
• Instrument compatibility for analysis: Compatible with LC-MS and LC-MS/MS workflows, with certified reference materials available for calibration and internal standards.

Products under ASSET™ EZ4 Dry Samplers 

• ASSET™ EZ4-NCO Dry Sampler: Sampling device for monomeric and oligomeric isocyanates in the ASSET™ EZ4 dry samplers for isocyanates family.
• ASSET™ EZ4-ICA Dry Sampler: Sampling device for isocyanic acid (ICA) and methyl isocyanate (MIC) in the ASSET™ EZ4 dry samplers for isocyanates family.

Chemical Express, with over 23 years of expertise in scientific and analytical solutions, is the official distributor of Merck in Thailand. Trust Chemical Express for easy access to ASSET™ EZ4 Dry Samplers and other related analytical products from Merck, ensuring your industrial hygiene and air monitoring requirements are met with certified precision.