BIOshell™ A160 Peptide U/HPLC Columns by Merck: High Resolution Peptide Separations

BIOshell™ A160 Peptide U/HPLC Columns by Merck utilize superficially porous, core-shell particle technology across a broad portfolio of particle sizes and phase chemistries, delivering a superior solution for fast and efficient peptide separations up to 20 kDa. These columns achieve higher resolutions and greater peak capacities at approximately 50% of the backpressure of sub-2 µm fully porous particle (FPP)-packed columns, and are compatible with all UHPLC and LC-MS instrumentation.

Key Features & Benefits of BIOshell™ A160 Peptide U/HPLC Columns

• Higher Resolution at Lower Backpressure: Achieves higher resolutions and greater peak capacities at approximately 50% of the backpressure generated by sub-2 µm fully porous particle-packed columns, reducing system stress while maintaining separation quality.
• Columns-in-Series Capability: The reduced backpressure allows multiple columns to be connected in series, further maximizing resolution and peak capacity for complex proteomic samples or tryptic digests.
• Broad Instrument Compatibility: Compatible with all UHPLC and LC-MS instrumentation, enabling seamless integration into existing laboratory setups without additional investment.
• Temperature Stability: Rated for use at temperatures up to 90°C.
• pH Stability Range: Designed to operate across a pH range of 1 to 8.
• Broad Portfolio of Particle Sizes and Phase Chemistries: Available in multiple particle sizes and phase chemistries to support separation of peptides up to 20 kDa.

Technical Specifications of BIOshell™ A160 Peptide U/HPLC Columns

Applications of BIOshell™ A160 Peptide U/HPLC Columns

• Tryptic Digests & Peptide Mapping: Optimized for high-resolution separation and analysis of tryptic digest samples in bottom-up proteomics workflows.
• Post-Translational Modifications (PTMs): Provides the peak capacity and selectivity required to resolve peptides differing only by phosphorylation, glycosylation, or other PTMs.
• Polypeptides up to 20 kDa: The 160 Å pore size ensures efficient mass transfer and retention of larger polypeptides, making these columns suitable for mid-size biotherapeutic characterization.

With over 23 years of expertise, Chemical Express is your trusted source for Merck’s BIOshell™ A160 Peptide U/HPLC Columns in Thailand. As the official distributor, we provide reliable access to the full range of BIOshell™ A160 columns, along with technical support and supply chain assurance for your analytical chromatography needs.