{"id":10496,"date":"2026-03-19T15:06:34","date_gmt":"2026-03-19T08:06:34","guid":{"rendered":"https:\/\/chemicalexpressth.com\/?p=10496"},"modified":"2026-08-11T15:40:55","modified_gmt":"2026-08-11T08:40:55","slug":"virusexpress-lentivirus-production-platform-merck","status":"publish","type":"post","link":"https:\/\/chemicalexpressth.com\/th\/articles\/product-guide-articles\/virusexpress-lentivirus-production-platform-merck\/","title":{"rendered":"VirusExpress\u00ae Lentivirus Production Platform by Merck \u2013 Scalable, GMP-compliant, High-Titer Lentiviral Vector Production"},"content":{"rendered":"<style>  .chx-standalone-article h1 {       color: #222 !important;       line-height: 1.2 !important;       font-weight: bold !important;       text-align: center !important;       margin-top: 40px !important;       margin-bottom: 30px !important;      text-transform: none !important;   }  .chx-standalone-article h2 {      color: #24326d !important;      font-weight: bold !important;     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.chx-standalone-article h2 { font-size: 18px !important; }  }<\/style>\n<div class=\"chx-standalone-article\">\n<div data-elementor-type=\"wp-post\" data-elementor-id=\"10496\" class=\"elementor elementor-10496\" data-elementor-post-type=\"post\">\n<div class=\"elementor-element elementor-element-7c6fcb73 e-flex e-con-boxed e-con e-parent\" data-id=\"7c6fcb73\" data-element_type=\"container\" data-e-type=\"container\">\n<div class=\"e-con-inner\">\n<div class=\"elementor-element elementor-element-581f5354 elementor-widget elementor-widget-text-editor\" data-id=\"581f5354\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n<div class=\"elementor-widget-container\">\n<h1>VirusExpress\u00ae Lentivirus Production Platform by Merck \u2013 Scalable, GMP-compliant, High-Titer Lentiviral Vector Production<\/h1>\n<div style=\"margin-bottom: 32px; text-align: center;\">  <img decoding=\"async\" class=\"lazyload\" src=\"data:image\/gif;base64,R0lGODlhAQABAIAAAAAAAP\/\/\/yH5BAEAAAAALAAAAAABAAEAAAIBRAA7\" data-src=\"https:\/\/chemicalexpressth.com\/wp-content\/uploads\/2026\/03\/VirusExpress\u00ae-Lentivirus-Production-Platform-by-Merck-\u2013-Scalable-GMP-compliant-High-Titer-Lentiviral-Vector-Production.png\" alt=\"VirusExpress\u00ae Lentivirus Production Platform by Merck \u2013 Scalable, GMP-compliant, High-Titer Lentiviral Vector Production\" style=\"width: 100%; max-width: 800px; height: auto; border-radius: 0px !important;\"><noscript><img decoding=\"async\" class=\"lazyload lazyload\" src=\"data:image\/gif;base64,R0lGODlhAQABAIAAAAAAAP\/\/\/yH5BAEAAAAALAAAAAABAAEAAAIBRAA7\" data-src=\"https:\/\/chemicalexpressth.com\/wp-content\/uploads\/2026\/03\/VirusExpress\u00ae-Lentivirus-Production-Platform-by-Merck-\u2013-Scalable-GMP-compliant-High-Titer-Lentiviral-Vector-Production.png\" alt=\"VirusExpress\u00ae Lentivirus Production Platform by Merck \u2013 Scalable, GMP-compliant, High-Titer Lentiviral Vector Production\" style=\"width: 100%; max-width: 800px; height: auto; border-radius: 0px !important;\"><noscript><img decoding=\"async\" class=\"lazyload lazyload lazyload\" src=\"data:image\/gif;base64,R0lGODlhAQABAIAAAAAAAP\/\/\/yH5BAEAAAAALAAAAAABAAEAAAIBRAA7\" data-src=\"https:\/\/chemicalexpressth.com\/wp-content\/uploads\/2026\/03\/VirusExpress\u00ae-Lentivirus-Production-Platform-by-Merck-\u2013-Scalable-GMP-compliant-High-Titer-Lentiviral-Vector-Production.png\" alt=\"VirusExpress\u00ae Lentivirus Production Platform by Merck \u2013 Scalable, GMP-compliant, High-Titer Lentiviral Vector Production\" style=\"width: 100%; max-width: 800px; height: auto; border-radius: 0px !important;\"><noscript><img data-src=\"https:\/\/chemicalexpressth.com\/wp-content\/uploads\/2026\/03\/VirusExpress\u00ae-Lentivirus-Production-Platform-by-Merck-\u2013-Scalable-GMP-compliant-High-Titer-Lentiviral-Vector-Production.png\" decoding=\"async\" class=\"lazyload lazyload lazyload\" src=\"data:image\/gif;base64,R0lGODlhAQABAIAAAAAAAP\/\/\/yH5BAEAAAAALAAAAAABAAEAAAIBRAA7\" alt=\"VirusExpress\u00ae Lentivirus Production Platform by Merck \u2013 Scalable, GMP-compliant, High-Titer Lentiviral Vector Production\" style=\"width: 100%; max-width: 800px; height: auto; border-radius: 0px !important;\"><noscript><img decoding=\"async\" class=\"lazyload lazyload lazyload\" src=\"https:\/\/chemicalexpressth.com\/wp-content\/uploads\/2026\/03\/VirusExpress\u00ae-Lentivirus-Production-Platform-by-Merck-\u2013-Scalable-GMP-compliant-High-Titer-Lentiviral-Vector-Production.png\" alt=\"VirusExpress\u00ae Lentivirus Production Platform by Merck \u2013 Scalable, GMP-compliant, High-Titer Lentiviral Vector Production\" style=\"width: 100%; max-width: 800px; height: auto; border-radius: 0px !important;\"><\/noscript><\/noscript><\/noscript><\/noscript><\/div>\n<p>Lentiviral vector production must meet demanding requirements for scalability, regulatory compliance, and fast process development, making a robust VirusExpress Lentivirus Production Platform especially valuable for gene therapy programs.<\/p>\n<h2>Why choose the VirusExpress Lentivirus Production Platform<\/h2>\n<ul>\n<li><b>Faster development timelines<\/b>: Reduces process development and scale-up time by approximately 40%.<\/li>\n<li><b>Accelerated therapy delivery<\/b>: Helps speed your therapy to patients.<\/li>\n<li><b>Scalable manufacturing readiness<\/b>: Supports production at clinically and commercially relevant scales with proven performance at 50 L.<\/li>\n<li><b>High titer output<\/b>: Achieves functional titers exceeding 4 \u00d7 10<sup>7<\/sup> TU\/mL.<\/li>\n<li><b>Regulatory support<\/b>: Provides robust quality documentation and full traceability to support regulatory filings and commercialization.<\/li>\n<li><b>Quality and compliance confidence<\/b>: Uses GMP-banked cells that are fully characterized and adventitious agent tested, with characterization in accordance with FDA cGMP regulations.<\/li>\n<li><b>Flexible deployment<\/b>: Can be implemented in your own facilities or through contract manufacturing capabilities.<\/li>\n<li><b>Development-stage licensing access<\/b>: Licenses are available for research, clinical, and commercial use depending on gene therapy development needs.<\/li>\n<\/ul>\n<h2>What\u2019s included in the VirusExpress Lentivirus Production Platform<\/h2>\n<ul>\n<li><b>Transfection-based upstream production architecture<\/b>: Lentiviral vector production is based on a transient transfection process for upstream manufacturing.<\/li>\n<li><b>Suspension-adapted cell line<\/b>: 293T Lentiviral Production Cells are adapted to suspension culture and optimized for production of lentiviral vectors for gene therapy applications.<\/li>\n<li><b>Cell line selection basis<\/b>: HEK293T VirusExpress\u00ae Cells were selected for higher lentivirus production using a PEI-based transient transfection method.<\/li>\n<li><b>Chemically defined medium<\/b>: The platform includes a chemically defined medium that is animal component-free and intended to address animal origin and supply chain concerns.<\/li>\n<li><b>User protocol package<\/b>: Comprehensive protocols cover seed train, at-scale transfection, and virus production.<\/li>\n<li><b>Manufacturing model<\/b>: The platform can be implemented within your own facilities or used with contract manufacturing capabilities.<\/li>\n<\/ul>\n<h2>Technical specifications for the VirusExpress Lentivirus Production Platform<\/h2>\n<ul>\n<li><strong>Proven process performance:<\/strong> demonstrated at 50 L scale<\/li>\n<li><strong>Functional titer:<\/strong> exceeding 4 \u00d7 10<sup>7<\/sup> TU\/mL<\/li>\n<li><strong>Process development and scale-up time reduction:<\/strong> approximately 40%<\/li>\n<li><strong>Characterization and regulatory references cited:<\/strong> FDA cGMP regulations 21 CFR 210, 211, 600, and 610<\/li>\n<\/ul>\n<h2>Applications and usage<\/h2>\n<ul>\n<li><strong>Upstream lentiviral production:<\/strong> Applied as a transfection-based solution specifically for upstream lentiviral production challenges.<\/li>\n<li><strong>Lentiviral vector manufacturing for gene therapy:<\/strong> Used with 293T Lentiviral Production Cells optimized for production of lentiviral vectors for gene therapy applications.<\/li>\n<li><strong>Suspension-based lentivirus production:<\/strong> Used for suspension-adapted lentivirus production workflows with a scalable upstream process.<\/li>\n<li><strong>Seed train to virus production workflow:<\/strong> Used across the process from seed train through at-scale transfection and virus production following the provided user protocols.<\/li>\n<li><strong>PEI-based transient transfection workflows:<\/strong> Compatible with PEI-based transient transfection methods for lentivirus production (PEI reagent supplied separately).<\/li>\n<li><strong>Large-scale bioreactor scale-up:<\/strong> Used for scale-up from shake flask culture to large-scale bioreactor production.<\/li>\n<\/ul>\n<h2>Products within the VirusExpress Lentivirus Production Platform<\/h2>\n<div class=\"res-table-wrapper\">\n<table>\n<tbody>\n<tr style=\"background-color:#24326D;\">\n<th style=\"color:#FFFFFF;\"><b>Product Description<\/b><\/th>\n<th style=\"color:#FFFFFF;\"><b>Storage Temperature<\/b><\/th>\n<th style=\"color:#FFFFFF;\"><b>Package Size<\/b><\/th>\n<\/tr>\n<tr>\n<td>VirusExpress\u00ae 293T Lentiviral Production Cells*<\/td>\n<td>-196 \u00b0C (Liquid N2 vapor phase)<\/td>\n<td>Vial format<\/td>\n<\/tr>\n<tr>\n<td>EX-CELL\u00ae CD HEK293 Viral Vector Medium, chemically defined, animal component-free, without L-glutamine, liquid, sterile-filtered, suitable for cell culture<\/td>\n<td>2-8 \u00b0C<\/td>\n<td>1000 mL in bottle<\/td>\n<\/tr>\n<tr>\n<td>EX-CELL\u00ae CD HEK293 Viral Vector Medium, chemically defined, animal component-free, without L-glutamine, liquid, sterile-filtered, suitable for cell culture<\/td>\n<td>2-8 \u00b0C<\/td>\n<td>10 L in bag<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p>Chemical Express, with over 23 years of expertise, is the official distributor of Merck in Thailand. Purchase VirusExpress\u00ae Lentivirus Production Platform and other related products from leading brands at Chemical Express to ensure quality, regulatory support and trusted supply for your gene therapy and bioprocessing needs.<\/p>\n<div style=\"text-align: center; margin-top: 64px; padding-bottom: 60px;\">\n<h3 style=\"margin-bottom: 8px;\">Have questions about the VirusExpress Lentivirus Production Platform or ready to order?<\/h3>\n<p>    Simply fill out our Inquiry Form or chat with us instantly on Line using the buttons below. <br \/>    We&#8217;re here to help!  <\/p>\n<div style=\"display: flex; justify-content: center; align-items: center; gap: 16px; flex-wrap: wrap; margin-bottom: 20px;\">    <a href=\"https:\/\/forms.zohopublic.com\/chatchawan1\/form\/WebsiteLeadFormINQUIRYFORM\/formperma\/oH9iL6pKdhH5WoJRahWoHuc5H_68uNoURPhu7cgU_rY?utm_source=n8n&amp;utm_medium=article&amp;utm_campaign=content2026_03_Product&amp;utm_content=virusexpress-lentivirus-production-platform-merck&amp;utm_term=inquiry_form&amp;utm_id=CONTENT_2026_03_Product\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"display: inline-flex; align-items: center; justify-content: center; padding: 14px 28px; background: #0b5ed7; color: #ffffff; text-decoration: none; border-radius: 8px; font-weight: 600; font-size: 16px; line-height: 1; white-space: nowrap;\" data-track=\"enquiry_cta\" data-intent=\"lead\">Submit Inquiry<\/a>    <a href=\"https:\/\/liff.line.me\/2004801212-fkTuG4m6?utm_source=website&#038;utm_medium=article&#038;utm_campaign=product_guide_2026&#038;utm_content=product_guide_article&#038;utm_term=add_line&#038;utm_id=product_guide_2026\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"display: inline-flex; align-items: center; justify-content: center; padding: 14px 28px; background: #06c755; color: #ffffff; text-decoration: none; border-radius: 8px; font-weight: 600; font-size: 16px; line-height: 1; white-space: nowrap;\" data-track=\"line_cta\" data-intent=\"add_line\">Add LINE<\/a>  <\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Order the VirusExpress\u00ae Lentiviral Production Platform from Chemical Express, the official Merck distributor in Thailand. 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