{"id":11048,"date":"2026-03-29T13:43:55","date_gmt":"2026-03-29T06:43:55","guid":{"rendered":"https:\/\/chemicalexpressth.com\/?p=11048"},"modified":"2026-08-11T15:46:15","modified_gmt":"2026-08-11T08:46:15","slug":"ascentis-express-c8-hplc-columns-merck","status":"publish","type":"post","link":"https:\/\/chemicalexpressth.com\/th\/articles\/product-guide-articles\/ascentis-express-c8-hplc-columns-merck\/","title":{"rendered":"Ascentis\u00ae Express C8 HPLC Columns by Merck \u2013 Enhanced Efficiency for Nonpolar Compound Separation"},"content":{"rendered":"<style>  .chx-standalone-article h1 {       color: #222 !important;       line-height: 1.2 !important;       font-weight: bold !important;       text-align: center !important;       margin-top: 40px !important;       margin-bottom: 30px !important;      text-transform: none !important;   }  .chx-standalone-article h2 {      color: #24326d !important;      font-weight: bold !important;      text-transform: none !important;      margin-top: 35px !important;      margin-bottom: 20px !important;  }  .chx-standalone-article .res-table-wrapper {       width: 100% !important;       overflow-x: auto !important;       -webkit-overflow-scrolling: touch !important;       margin-bottom: 25px !important;   }  .chx-standalone-article table {       min-width: 600px !important;       width: 100% !important;   }  @media only screen and (min-width: 1025px) {    .chx-standalone-article h1 { font-size: 30px !important; }    .chx-standalone-article h2 { font-size: 24px !important; }  }  @media only screen and (max-width: 1024px) {    .chx-standalone-article h1 { font-size: 22px !important; margin-top: 30px !important; margin-bottom: 25px !important; }    .chx-standalone-article h2 { font-size: 20px !important; }  }  @media only screen and (max-width: 480px) {    .chx-standalone-article h1 { font-size: 15px !important; margin-top: 20px !important; margin-bottom: 20px !important; }    .chx-standalone-article h2 { font-size: 18px !important; }  }<\/style>\n<div class=\"chx-standalone-article\">\n<div data-elementor-type=\"wp-post\" data-elementor-id=\"11048\" class=\"elementor elementor-11048\" data-elementor-post-type=\"post\">\n<div class=\"elementor-element elementor-element-718e3222 e-flex e-con-boxed e-con e-parent\" data-id=\"718e3222\" data-element_type=\"container\" data-e-type=\"container\">\n<div class=\"e-con-inner\">\n<div class=\"elementor-element elementor-element-775d6372 elementor-widget elementor-widget-text-editor\" data-id=\"775d6372\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n<div class=\"elementor-widget-container\">\n<h1>Ascentis\u00ae Express C8 HPLC Columns by Merck \u2013 Enhanced Efficiency for Nonpolar Compound Separation<\/h1>\n<div style=\"margin-bottom: 32px; text-align: center;\"><img decoding=\"async\" class=\"lazyload\" style=\"width: 100%; max-width: 800px; height: auto; border-radius: 0px !important;\" src=\"data:image\/gif;base64,R0lGODlhAQABAIAAAAAAAP\/\/\/yH5BAEAAAAALAAAAAABAAEAAAIBRAA7\" data-src=\"https:\/\/chemicalexpressth.com\/wp-content\/uploads\/2026\/03\/Ascentis\u00ae-Express-C8-HPLC-Columns-by-Merck-\u2013-Enhanced-Efficiency-for-Nonpolar-Compound-Separation.png\" alt=\"Ascentis\u00ae Express C8 HPLC Columns by Merck \u2013 Enhanced Efficiency for Nonpolar Compound Separation\"><noscript><img decoding=\"async\" class=\"lazyload lazyload\" style=\"width: 100%; max-width: 800px; height: auto; border-radius: 0px !important;\" src=\"data:image\/gif;base64,R0lGODlhAQABAIAAAAAAAP\/\/\/yH5BAEAAAAALAAAAAABAAEAAAIBRAA7\" data-src=\"https:\/\/chemicalexpressth.com\/wp-content\/uploads\/2026\/03\/Ascentis\u00ae-Express-C8-HPLC-Columns-by-Merck-\u2013-Enhanced-Efficiency-for-Nonpolar-Compound-Separation.png\" alt=\"Ascentis\u00ae Express C8 HPLC Columns by Merck \u2013 Enhanced Efficiency for Nonpolar Compound Separation\"><noscript><img decoding=\"async\" class=\"lazyload lazyload lazyload\" style=\"width: 100%; max-width: 800px; height: auto; border-radius: 0px !important;\" src=\"data:image\/gif;base64,R0lGODlhAQABAIAAAAAAAP\/\/\/yH5BAEAAAAALAAAAAABAAEAAAIBRAA7\" data-src=\"https:\/\/chemicalexpressth.com\/wp-content\/uploads\/2026\/03\/Ascentis\u00ae-Express-C8-HPLC-Columns-by-Merck-\u2013-Enhanced-Efficiency-for-Nonpolar-Compound-Separation.png\" alt=\"Ascentis\u00ae Express C8 HPLC Columns by Merck \u2013 Enhanced Efficiency for Nonpolar Compound Separation\"><noscript><img decoding=\"async\" class=\"lazyload lazyload lazyload lazyload\" style=\"width: 100%; max-width: 800px; height: auto; border-radius: 0px !important;\" src=\"data:image\/gif;base64,R0lGODlhAQABAIAAAAAAAP\/\/\/yH5BAEAAAAALAAAAAABAAEAAAIBRAA7\" data-src=\"https:\/\/chemicalexpressth.com\/wp-content\/uploads\/2026\/03\/Ascentis\u00ae-Express-C8-HPLC-Columns-by-Merck-\u2013-Enhanced-Efficiency-for-Nonpolar-Compound-Separation.png\" alt=\"Ascentis\u00ae Express C8 HPLC Columns by Merck \u2013 Enhanced Efficiency for Nonpolar Compound Separation\"><noscript><img decoding=\"async\" class=\"lazyload lazyload lazyload lazyload lazyload\" style=\"width: 100%; max-width: 800px; height: auto; border-radius: 0px !important;\" src=\"data:image\/gif;base64,R0lGODlhAQABAIAAAAAAAP\/\/\/yH5BAEAAAAALAAAAAABAAEAAAIBRAA7\" data-src=\"https:\/\/chemicalexpressth.com\/wp-content\/uploads\/2026\/03\/Ascentis\u00ae-Express-C8-HPLC-Columns-by-Merck-\u2013-Enhanced-Efficiency-for-Nonpolar-Compound-Separation.png\" alt=\"Ascentis\u00ae Express C8 HPLC Columns by Merck \u2013 Enhanced Efficiency for Nonpolar Compound Separation\"><noscript><img decoding=\"async\" class=\"lazyload lazyload lazyload lazyload lazyload lazyload\" style=\"width: 100%; max-width: 800px; height: auto; border-radius: 0px !important;\" src=\"data:image\/gif;base64,R0lGODlhAQABAIAAAAAAAP\/\/\/yH5BAEAAAAALAAAAAABAAEAAAIBRAA7\" data-src=\"https:\/\/chemicalexpressth.com\/wp-content\/uploads\/2026\/03\/Ascentis\u00ae-Express-C8-HPLC-Columns-by-Merck-\u2013-Enhanced-Efficiency-for-Nonpolar-Compound-Separation.png\" alt=\"Ascentis\u00ae Express C8 HPLC Columns by Merck \u2013 Enhanced Efficiency for Nonpolar Compound Separation\"><noscript><img decoding=\"async\" class=\"lazyload lazyload lazyload lazyload lazyload lazyload lazyload\" style=\"width: 100%; max-width: 800px; height: auto; border-radius: 0px !important;\" src=\"data:image\/gif;base64,R0lGODlhAQABAIAAAAAAAP\/\/\/yH5BAEAAAAALAAAAAABAAEAAAIBRAA7\" data-src=\"https:\/\/chemicalexpressth.com\/wp-content\/uploads\/2026\/03\/Ascentis\u00ae-Express-C8-HPLC-Columns-by-Merck-\u2013-Enhanced-Efficiency-for-Nonpolar-Compound-Separation.png\" alt=\"Ascentis\u00ae Express C8 HPLC Columns by Merck \u2013 Enhanced Efficiency for Nonpolar Compound Separation\"><noscript><img data-src=\"https:\/\/chemicalexpressth.com\/wp-content\/uploads\/2026\/03\/Ascentis\u00ae-Express-C8-HPLC-Columns-by-Merck-\u2013-Enhanced-Efficiency-for-Nonpolar-Compound-Separation.png\" decoding=\"async\" class=\"lazyload lazyload lazyload lazyload lazyload lazyload lazyload\" style=\"width: 100%; max-width: 800px; height: auto; border-radius: 0px !important;\" src=\"data:image\/gif;base64,R0lGODlhAQABAIAAAAAAAP\/\/\/yH5BAEAAAAALAAAAAABAAEAAAIBRAA7\" alt=\"Ascentis\u00ae Express C8 HPLC Columns by Merck \u2013 Enhanced Efficiency for Nonpolar Compound Separation\"><noscript><img decoding=\"async\" class=\"lazyload lazyload lazyload lazyload lazyload lazyload lazyload\" style=\"width: 100%; max-width: 800px; height: auto; border-radius: 0px !important;\" src=\"https:\/\/chemicalexpressth.com\/wp-content\/uploads\/2026\/03\/Ascentis\u00ae-Express-C8-HPLC-Columns-by-Merck-\u2013-Enhanced-Efficiency-for-Nonpolar-Compound-Separation.png\" alt=\"Ascentis\u00ae Express C8 HPLC Columns by Merck \u2013 Enhanced Efficiency for Nonpolar Compound Separation\"><\/noscript><\/noscript><\/noscript><\/noscript><\/noscript><\/noscript><\/noscript><\/noscript><\/div>\n<p>Laboratories face challenges separating less hydrophobic compounds or achieving faster retention when C18 columns fall short. Ascentis\u00ae Express C8 columns with Superficially Porous Silica Particles technology deliver superior speed, efficiency, and reliable results for demanding analytical applications. Explore how these columns streamline nonpolar compound analysis and meet strict industry demands.<\/p>\n<h2>Why Choose Ascentis\u00ae Express C8<\/h2>\n<ul>\n<li><b>Higher throughput<\/b>: Delivers higher speed and efficiency than fully porous particles of the same size.<\/li>\n<li><b>System productivity<\/b>: Converts an HPLC system into a fast HPLC workhorse with maximum speed and performance.<\/li>\n<li><b>Reliable analytical consistency<\/b>: Supports inert, stable, and reproducible operation for dependable results.<\/li>\n<li><b>Retention control for challenging analytes<\/b>: Provides enhanced retention for less hydrophobic compounds.<\/li>\n<li><b>Shorter analysis time when C18 retention is excessive<\/b>: Enables faster separation when retention on C18 is too long.<\/li>\n<li><b>Better fit for strongly retained nonpolar compounds<\/b>: Addresses separations where nonpolar compounds are retained too strongly by a traditional C18 column.<\/li>\n<li><b>Preparative loading support<\/b>: Offers suitability for preparative loading capacity.<\/li>\n<\/ul>\n<h2>Key Features of Ascentis\u00ae Express C8<\/h2>\n<ul>\n<li><b>Particle Technology<\/b>: Superficially Porous Silica Particles using Fused-Core\u00ae Technology.<\/li>\n<li><b>Bonded Phase Silica<\/b>: Type B silica bonded phase architecture.<\/li>\n<li><b>Phase Chemistry<\/b>: Dimethyloctyl.<\/li>\n<li><b>Functional Role<\/b>: C8 column option for method selection when a C18 does not provide the desired separation.<\/li>\n<\/ul>\n<h2>Ascentis\u00ae Express C8 Technical Specifications<\/h2>\n<div class=\"res-table-wrapper\">\n<table style=\"width: 100%; border-collapse: collapse; font-family: ; border: 1px solid #ddd;\">\n<thead>\n<tr style=\"background-color: #24326d; color: #ffffff;\">\n<th colspan=\"2\" style=\"padding: 12px; border: 1px solid #ddd; text-align: left; font-size: 1.1em;\">        Ascentis\u00ae Express C8 Specifications      <\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding: 10px; border: 1px solid #ddd; font-weight: bold; width: 35%;\">Silica:<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">Type B (High purity silica)<\/td>\n<\/tr>\n<tr style=\"background-color: #f9f9f9;\">\n<td style=\"padding: 10px; border: 1px solid #ddd; font-weight: bold;\">Particle Platform:<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">Superficially porous particles (SPP)<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 10px; border: 1px solid #ddd; font-weight: bold;\">Phase Chemistry:<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">Dimethyloctyl<\/td>\n<\/tr>\n<tr style=\"background-color: #f9f9f9;\">\n<td style=\"padding: 10px; border: 1px solid #ddd; font-weight: bold;\">Particle Size:<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">2.0 \u00b5m \/ 2.7 \u00b5m \/ 5.0 \u00b5m<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 10px; border: 1px solid #ddd; font-weight: bold;\">Pore Size:<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">90 \u00c5<\/td>\n<\/tr>\n<tr style=\"background-color: #f9f9f9;\">\n<td style=\"padding: 10px; border: 1px solid #ddd; font-weight: bold;\">Carbon Load:<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">4.8% \/ 5.4% \/ 3.7%<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 10px; border: 1px solid #ddd; font-weight: bold;\">Surface Area:<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">120 m\u00b2\/g \/ 135 m\u00b2\/g \/ 90 m\u00b2\/g<\/td>\n<\/tr>\n<tr style=\"background-color: #f9f9f9;\">\n<td style=\"padding: 10px; border: 1px solid #ddd; font-weight: bold;\">pH Range:<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">2 &#8211; 9<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 10px; border: 1px solid #ddd; font-weight: bold;\">Max Temperature at Low pH:<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">60 \u00b0C<\/td>\n<\/tr>\n<tr style=\"background-color: #f9f9f9;\">\n<td style=\"padding: 10px; border: 1px solid #ddd; font-weight: bold;\">Max Temperature at High pH:<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">40 \u00b0C<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 10px; border: 1px solid #ddd; font-weight: bold;\">Endcapped:<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">Yes<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<h2>Application and Usage of Ascentis\u00ae Express C8<\/h2>\n<ul>\n<li>Method adjustment when a C18 does not give the desired separation.<\/li>\n<li>Sample analysis for compounds that are difficult to retain or resolve on a C18.<\/li>\n<li>Use with nonpolar compounds that are retained too strongly by a traditional C18 column.<\/li>\n<li>Fast separation of dyes.<\/li>\n<li>Analysis of spice mixtures to determine adulteration in the context of Sudan I contamination incidents.<\/li>\n<\/ul>\n<p>With more than 23 years of expertise, Chemical Express is the official distributor of Merck in Thailand. Order Ascentis\u00ae Express C8 columns and other Merck analytical products from Chemical Express to ensure access to genuine, high-performance solutions for your chromatography needs.<\/p>\n<div style=\"text-align: center; margin-top: 64px; padding-bottom: 60px;\">\n<h3 style=\"margin-bottom: 8px;\">Have questions about Ascentis\u00ae Express C8<br \/>or ready to order?<\/h3>\n<p>Simply fill out our Inquiry Form or chat with us instantly on Line using the buttons below.<br \/>We&#8217;re here to help!<\/p>\n<div style=\"display: flex; justify-content: center; align-items: center; gap: 16px; flex-wrap: wrap; margin-bottom: 20px;\"><a style=\"display: inline-flex; align-items: center; justify-content: center; padding: 14px 28px; background: #0b5ed7; color: #ffffff; text-decoration: none; border-radius: 8px; font-weight: 600; font-size: 16px; line-height: 1; white-space: nowrap;\" 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