{"id":9654,"date":"2026-03-01T19:38:55","date_gmt":"2026-03-01T12:38:55","guid":{"rendered":"https:\/\/chemicalexpressth.com\/?p=9654"},"modified":"2026-08-11T15:35:28","modified_gmt":"2026-08-11T08:35:28","slug":"tlc-silica-gel-60-g-plates-gypsum-merck","status":"publish","type":"post","link":"https:\/\/chemicalexpressth.com\/th\/articles\/product-guide-articles\/tlc-silica-gel-60-g-plates-gypsum-merck\/","title":{"rendered":"TLC Silica Gel 60 G Plates with Gypsum by Merck \u2013 Premium Compliance for Pharmacopoeia &#038; Analytical Chromatography"},"content":{"rendered":"<style>  .chx-standalone-article h1 {       color: #222 !important;       line-height: 1.2 !important;       font-weight: bold !important;       text-align: center !important;       margin-top: 40px !important;       margin-bottom: 30px !important;      text-transform: none !important;   }  .chx-standalone-article h2 {      color: #24326d !important;      font-weight: bold !important;      text-transform: none !important;      margin-top: 35px !important;      margin-bottom: 20px !important;  }  .chx-standalone-article .res-table-wrapper {       width: 100% !important;       overflow-x: auto !important;       -webkit-overflow-scrolling: touch !important;       margin-bottom: 25px !important;   }  .chx-standalone-article table {       min-width: 600px !important;       width: 100% !important;   }  @media only screen and (min-width: 1025px) {    .chx-standalone-article h1 { font-size: 30px !important; }    .chx-standalone-article h2 { font-size: 24px !important; }  }  @media only screen and (max-width: 1024px) {    .chx-standalone-article h1 { font-size: 22px !important; margin-top: 30px !important; margin-bottom: 25px !important; }    .chx-standalone-article h2 { font-size: 20px !important; }  }  @media only screen and (max-width: 480px) {    .chx-standalone-article h1 { font-size: 15px !important; margin-top: 20px !important; margin-bottom: 20px !important; }    .chx-standalone-article h2 { font-size: 18px !important; }  }<\/style>\n<div class=\"chx-standalone-article\">\n<h1>TLC Silica Gel 60 G Plates with Gypsum by Merck: Premium Compliance for Pharmacopoeia &amp; Analytical Chromatography<\/h1>\n<div style=\"margin-bottom: 32px; text-align: center;\"><img decoding=\"async\" class=\"lazyload\" style=\"width: 100%; max-width: 800px; height: auto; border-radius: 0px !important;\" src=\"data:image\/gif;base64,R0lGODlhAQABAIAAAAAAAP\/\/\/yH5BAEAAAAALAAAAAABAAEAAAIBRAA7\" data-src=\"https:\/\/chemicalexpressth.com\/wp-content\/uploads\/2026\/03\/image-2.jpg\" alt=\"TLC Silica Gel 60 G Plates with Gypsum by Merck \u2013 Premium Compliance for Pharmacopoeia &amp; Analytical Chromatography\" \/><noscript><img decoding=\"async\" class=\"lazyload lazyload\" style=\"width: 100%; max-width: 800px; height: auto; border-radius: 0px !important;\" src=\"data:image\/gif;base64,R0lGODlhAQABAIAAAAAAAP\/\/\/yH5BAEAAAAALAAAAAABAAEAAAIBRAA7\" data-src=\"https:\/\/chemicalexpressth.com\/wp-content\/uploads\/2026\/03\/image-2.jpg\" alt=\"TLC Silica Gel 60 G Plates with Gypsum by Merck \u2013 Premium Compliance for Pharmacopoeia &amp; Analytical Chromatography\" \/><noscript><img decoding=\"async\" class=\"lazyload lazyload lazyload\" style=\"width: 100%; max-width: 800px; height: auto; border-radius: 0px !important;\" src=\"data:image\/gif;base64,R0lGODlhAQABAIAAAAAAAP\/\/\/yH5BAEAAAAALAAAAAABAAEAAAIBRAA7\" data-src=\"https:\/\/chemicalexpressth.com\/wp-content\/uploads\/2026\/03\/image-2.jpg\" alt=\"TLC Silica Gel 60 G Plates with Gypsum by Merck \u2013 Premium Compliance for Pharmacopoeia &amp; Analytical Chromatography\" \/><noscript><img data-src=\"https:\/\/chemicalexpressth.com\/wp-content\/uploads\/2026\/03\/image-2.jpg\" decoding=\"async\" class=\"lazyload lazyload lazyload\" style=\"width: 100%; max-width: 800px; height: auto; border-radius: 0px !important;\" src=\"data:image\/gif;base64,R0lGODlhAQABAIAAAAAAAP\/\/\/yH5BAEAAAAALAAAAAABAAEAAAIBRAA7\" alt=\"TLC Silica Gel 60 G Plates with Gypsum by Merck \u2013 Premium Compliance for Pharmacopoeia &amp; Analytical Chromatography\" \/><noscript><img decoding=\"async\" class=\"lazyload lazyload lazyload\" style=\"width: 100%; max-width: 800px; height: auto; border-radius: 0px !important;\" src=\"https:\/\/chemicalexpressth.com\/wp-content\/uploads\/2026\/03\/image-2.jpg\" alt=\"TLC Silica Gel 60 G Plates with Gypsum by Merck \u2013 Premium Compliance for Pharmacopoeia &amp; Analytical Chromatography\"><\/noscript><\/noscript><\/noscript><\/noscript><\/div>\n<p>Achieve accurate, reproducible chromatography required by the European Pharmacopoeia with TLC Silica Gel 60 G Plates with Gypsum from Merck.<\/p>\n<p>Specifically designed to meet strict QA\/QC demands in pharmaceutical analysis, these plates provide consistent, precise separation performance for critical assays. Below you will find key product details, compliance information, and representative application examples used in regulated laboratories.<\/p>\n<h2>Benefits of the product<\/h2>\n<ul>\n<li>Designed for QA\/QC laboratories running European Pharmacopoeia (Ph. Eur.) monograph methods that specifically require TLC plates with gypsum instead of classical plates with organic binders.<\/li>\n<li>Supports pharmacopoeial method adherence by complying with the International Pharmacopoeia.<\/li>\n<li>Helps align routine TLC workflows with Ph. Eu. expectations because the plates are mentioned in about 200 monograph methods described in the European Pharmacopoeia (Ph. Eu.).<\/li>\n<li>Provides confidence in regulated testing by satisfying the TLC performance test requirements of the European Pharmacopoeia, in addition to in-house standard QC tests.<\/li>\n<li>Delivers separation quality demonstrated by meeting the European Pharmacopoeia TLC performance test outcome of four clearly separated spots.<\/li>\n<\/ul>\n<h2>Features of the product<\/h2>\n<ul>\n<li><b>Product type:<\/b> Thin layer chromatography (TLC) plates formulated as TLC silica gel 60 G plates with gypsum.<\/li>\n<li><b>Adsorbent layer:<\/b> Silica gel 60 as the adsorbent layer.<\/li>\n<li><b>Pore structure:<\/b> Silica gel with a nominal pore size of 60 \u00c5.<\/li>\n<li><b>Binder material:<\/b> Gypsum incorporated as the binder in the silica gel layer.<\/li>\n<li><b>Gypsum form:<\/b> Present as calcium sulfate hemihydrate (1\/2CaSO4).<\/li>\n<\/ul>\n<h2>Technical Specifications<\/h2>\n<ul>\n<li><strong>Adsorbent pore size<\/strong>: 60 \u00c5 (silica gel 60 \u00c5)<\/li>\n<li><strong>TLC performance test conditions<\/strong>: TLC performance test solution R (Reagent 1116600); application volume 10 \u03bcL for a normal TLC plate and 1 \u03bcL to 2 \u03bcL for a fine particle size plate; mobile phase 20 volumes of methanol R and 80 volumes of toluene R; development length equal to two thirds of the plate height<\/li>\n<li><strong>Performance test results (hRf values)<\/strong>:\n<ul>\n<li><strong>Separation<\/strong>: 4 clearly separated spots (Specification: 4 clearly separated spots; Typical value: passed)<\/li>\n<li><strong>Bromocresol green<\/strong>: Specification &lt;15; Typical value 5<\/li>\n<li><strong>Methyl orange<\/strong>: Specification 10 &#8211; 25; Typical value 10<\/li>\n<li><strong>Methyl red<\/strong>: Specification 35 &#8211; 55; Typical value 38<\/li>\n<li><strong>Sudan red<\/strong>: Specification 75 &#8211; 98; Typical value 82<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h2>Application and usage<\/h2>\n<ul>\n<li><strong>Recommended use context:<\/strong> For QA\/QC laboratories using European Pharmacopoeia (Ph. Eur.) monograph methods that require TLC plates with gypsum instead of classical plates with organic binders.<\/li>\n<li><strong>European Pharmacopoeia TLC performance test:<\/strong> Suitable for the TLC performance test involving application of TLC performance test solution R (Reagent 1116600) and development in a mobile phase of methanol R and toluene R to two thirds of the plate height, with the outcome assessed by the presence of four clearly separated spots.<\/li>\n<li><strong>Identification test for Atenolol and Chlorthalidone in tablets (Ph. Eur. monograph conditions):<\/strong>\n<ul>\n<li><strong>TLC plate:<\/strong> Silica Gel 60 G F254, 20 x 20 cm<\/li>\n<li><strong>Application volume:<\/strong> 5 \u03bcL of each solution<\/li>\n<li><strong>Detection:<\/strong> UV @ 254 nm<\/li>\n<li><strong>Mobile phase:<\/strong> 18 M ammonia and n-butanol 30:150 (v\/v)<\/li>\n<li><strong>Plate development:<\/strong> Line the walls of the chromatographic tank with filter paper; pour a sufficient quantity of mobile phase into the chromatographic tank; saturate the chromatographic tank, replace the lid and allow to stand at 20 to 25\u00b0C for 1 hr; apply the prescribed volume of the solutions in sufficiently small portions to obtain bands at an appropriate distance from the lower edge.<\/li>\n<li><strong>Migration distance:<\/strong> 15 cm<\/li>\n<li><strong>Drying:<\/strong> In air<\/li>\n<li><strong>Standard preparation:<\/strong> 1.0% (w\/v) of atenolol in 0.25% (w\/v) of chlorthalidone in methanol<\/li>\n<li><strong>Sample preparation:<\/strong> Remove any film coating on the tablet powder and shake the quantity of powered tablet containing 0.1 g of atenolol with 10 mL of methanol for 15 minutes and filter.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h2>List of products under TLC Silica Gel 60 G Plates with Gypsum<\/h2>\n<div class=\"res-table-wrapper\">\n<table style=\"width: 100%; border-collapse: collapse; margin-bottom: 24px;\">\n<thead>\n<tr>\n<th style=\"border: 1px solid #ddd; padding: 8px; text-align: left;\">Product code<\/th>\n<th style=\"border: 1px solid #ddd; padding: 8px; text-align: left;\">Product name<\/th>\n<th style=\"border: 1px solid #ddd; padding: 8px; text-align: left;\">Format \/ description<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"border: 1px solid #ddd; padding: 8px;\"><i>1.00390<\/i><\/td>\n<td style=\"border: 1px solid #ddd; padding: 8px;\"><i>TLC Silica gel 60G F254 25 Glass plates 20 x 20 cm<\/i><\/td>\n<td style=\"border: 1px solid #ddd; padding: 8px;\">Glass support (silica gel coated), plate L \u00d7 W 20 cm \u00d7 20 cm, suitable for thin layer chromatography (TLC), pkg of 25 plates, fluorometric<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 1px solid #ddd; padding: 8px;\"><i>99571<\/i><\/td>\n<td style=\"border: 1px solid #ddd; padding: 8px;\"><i>TLC Silica gel 60 plates with fluorescent indicator<\/i><\/td>\n<td style=\"border: 1px solid #ddd; padding: 8px;\">L \u00d7 W 20 cm \u00d7 20 cm, silica gel 60 matrix, fluorescent indicator<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p>Trust Chemical Express, an official distributor with over 23 years of experience, to supply Merck TLC Silica Gel 60 G Plates with Gypsum and related analytical chromatography products.<\/p>\n<div style=\"text-align: center; margin-top: 64px; padding-bottom: 60px;\">\n<h3 style=\"margin-bottom: 8px;\">Need technical guidance or a quote for TLC Silica Gel 60 G Plates with Gypsum?<\/h3>\n<p>Simply fill out our Inquiry Form or chat with us instantly on Line using the buttons below.<br \/>Our team is ready to support your TLC method and product selection.<\/p>\n<div style=\"display: flex; justify-content: center; align-items: center; gap: 16px; flex-wrap: wrap; margin-bottom: 20px;\"><a style=\"display: inline-flex; align-items: center; justify-content: center; padding: 14px 28px; background: #0b5ed7; color: #ffffff; text-decoration: none; border-radius: 8px; font-weight: 600; font-size: 16px; line-height: 1; white-space: nowrap;\" href=\"https:\/\/forms.zohopublic.com\/chatchawan1\/form\/WebsiteLeadFormINQUIRYFORM\/formperma\/oH9iL6pKdhH5WoJRahWoHuc5H_68uNoURPhu7cgU_rY?utm_source=n8n&amp;utm_medium=article&amp;utm_campaign=content2026_02_Product&amp;utm_content=tlc-silica-gel-60-g-plates-gypsum-merck&amp;utm_term=inquiry_form&amp;utm_id=CONTENT_2026_01_Product\" target=\"_blank\" rel=\"noopener noreferrer\" data-track=\"enquiry_cta\" data-intent=\"lead\">Submit Inquiry<\/a><br \/><a style=\"display: inline-flex; align-items: center; justify-content: center; padding: 14px 28px; background: #06c755; color: #ffffff; text-decoration: none; border-radius: 8px; font-weight: 600; font-size: 16px; line-height: 1; white-space: nowrap;\" href=\"https:\/\/liff.line.me\/2004801212-fkTuG4m6?utm_source=website&#038;utm_medium=article&#038;utm_campaign=product_guide_2026&#038;utm_content=product_guide_article&#038;utm_term=add_line&#038;utm_id=product_guide_2026\" target=\"_blank\" rel=\"noopener noreferrer\" data-track=\"line_cta\" data-intent=\"add_line\">Add LINE<\/a><\/div>\n<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Premium Merck TLC Silica Gel 60 G Plates with Gypsum\u2014ideal for European Pharmacopoeia QA\/QC chromatography. 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