MultiScreen® HTS Filter Plates by Merck: Advanced Lab Filtration for High Throughput Automation and Reliable Results

Demanding automated workflows require filter plates that deliver reliability, consistency, and high throughput. MultiScreen® HTS Filter Plates by Merck are engineered for automated workstations, supporting drug discovery and preclinical research with features that prevent cross-contamination, improve plate handling, and enhance assay performance. Discover how these plates can streamline your filtration and culture processes.

Benefits of MultiScreen® HTS Filter Plates

Automation compatibility: Supports high throughput workflows on automated workstations with compatibility for automated handling and reading systems.
Reliable isolation: Minimizes well-to-well interference during incubation and filtrate transfer with stated cross talk event frequency of less than 0.04%.
Assay performance support: MultiScreen®HTS+ plates provide enhanced washing with reduced background and improved signal-to-noise ratios.
Research workflow fit: Provides a complete solution for drug discovery and life science research across multiple assay types.
Direct counting suitability: Supports accurate and reliable detection for liquid scintillation microplate counting in specified MultiScreen HTS formats (see product list notes for compatible plates).

Features and Design of MultiScreen® HTS Filter Plates

Automation-oriented plate architecture: Specifically developed for high throughput use with automated workstations.
Standardized format: The 96-well plates are designed to standardized dimensions and meet ANSI/SBS plate specifications.
Plate formats: Available in 96-well and 384-well formats.
Sidewall construction: Firm, rigid sidewalls are aligned for handling by robotic gripper arms.
Barcode labeling area: Sidewall surfaces accommodate barcode labels.
Well isolation design: Individual wells are sealed and use individually sealed filter discs.
Underdrain access: A removable patented underdrain provides full access to membranes.
Underdrain protection: The plate design protects the underdrain and eliminates surface contact with individual well drip directors.
Skirt configuration: A plastic skirt enables stacking directly with collection plates and improves the vacuum seal when used with a Millipore® vacuum manifold.
Membrane and plastic options: A broad selection of membranes and plastics is available, with custom requests accepted for non-standard combinations.
MultiScreen®HTS+ backing: A unique nylon mesh backing is included in MultiScreen®HTS+ plates.
Membrane access options: The plate range includes unique membrane access options.
Color availability: MultiScreen®P HTS filter plates are available in clear, opaque, and white.

Technical Specifications of MultiScreen HTS 96-well Filter Plates

Materials of construction: Broad range of membranes and plastics available. See ordering information or refer to the user guide for detailed material options.
Membrane Area: 0.26 cm²
Well Volume: Recommended 50-250 μL (Maximum 300 μL)
Nominal Plate Dimensions (length x width x depth): 127.8 mm x 85.5 mm x 14.4 mm
Operating Conditions: Vacuum – Recommended 9″ Hg (Maximum 18″ Hg) Centrifuge – Recommended 1000 x g (Maximum 3000 x g)
Average Holdup Volume of 200 μL Sample: By vacuum at 9″ Hg for 30s
Average Holdup Volume of 200 μL Sample: By centrifuge at 1000 x g for 5 mins Durapore® PVDF 6 µL/well Durapore® PVDF 5 µL/well

Applications and Usage of MultiScreen HTS Filter Plates

Drug discovery: Used as part of high throughput workflows in drug discovery.
Life science research: Used for life science research workflows requiring filter plate processing.
Receptor-ligand binding: Supported within the MultiScreen® HTS filter plate application range.
General sample preparation: Used for filtration-based sample preparation in plate format.
ELISpot: The removable underdrain provides membrane access for ELISpot applications.
Enzyme activity assays: Supported within the stated application family of MultiScreen® HTS filter plates.
Bead-based assays: Included among the supported assay applications.
Whole organism visualization: The removable underdrain provides membrane access for whole organism visualization.
Radioisotope detection: The removable underdrain provides membrane access for radioisotope detection.
Filtration-based solubility determination: MultiScreen® Solubility filter plates are optimized in HTS format for filtration-based solubility determination.
Liquid scintillation microplate counting: Stated as an ideal use for MultiScreen® HTS plate formats.

MultiScreen HTS Filter Plates Product List

Description	Pore Size (µm)	Plate Material/ Plate Color	Sterility (Sterile = S)	Qty/Pk
MultiScreen®_HTS with hydrophilic Durapore membrane (PVDF)
	0.22	acrylic	–	10
			–	50
			S	10
	0.22	Barex®/TiO₂	–	50
	0.45	styrene	–	10
			–	50
			S	10
	0.45	Barex/TiO₂	–	10
			–	50
			S	10
	0.65	styrene	–	10
	0.65	styrene	–	50
	0.65	Barex/TiO₂	–	50
	1.2	styrene	–	10
			–	50
			S	10
	1.2	Barex/TiO₂	–	50
MultiScreen®_HTS with hydrophobic Immobilon-P membrane (PVDF)
	0.45	acrylic	–	10
			–	50
			S	10
	0.45	acrylic white	–	10
	0.45	Barex/TiO₂	–	10
	0.45	Barex/TiO₂	–	50
MultiScreen®_HTS with hydrophilic MCE
	0.45	styrene	–	10
			–	50
			S	10
	0.45	Barex/TiO₂	–	50
	0.45	Barex/TiO₂		S	10
MultiScreen® with track-etched polycarbonate
MultiScreen®_HTS Solubility Assay System	0.4	styrene	–	10
MultiScreen®_HTS with glass fiber filter and PVDF support
FB w/0.65		Barex/TiO₂	–	10
FB w/0.65		Barex/TiO₂	–	50
FC w/0.65		Barex/TiO₂	–	10
FC w/0.65		Barex/TiO₂	–	50

Chemical Express, with more than 23 years of experience in laboratory and industrial supply, is the official distributor of Merck in Thailand. Find MultiScreen HTS Filter Plates and a broad range of related products from trusted brands at Chemical Express to support your research and automation needs in Thailand.

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