Merck Amicon® Ultrafiltration Devices

When downstream quality matters, it’s essential to rely on the best upstream tools. From sample preparation to final concentration, Amicon® ultrafiltration devices from Merck Millipore excel in delivering high yields and purity, ensuring consistent and reproducible results. Whether you’re concentrating dilute samples, performing buffer exchange or desalting, purifying proteins from complex mixtures or more, the devices simplify the workflow, making protein sample preparation a breeze.

With Amicon® ultrafiltration devices, you can achieve crystal-clear data from every bit of protein, effortlessly. 

Chemical Express distributes Amicon® ultrafiltration devices from Merck across Thailand.

ChemEx เป็นผู้จัดจำหน่ายผลิตภัณฑ์ของ Merck

Amicon® Ultra Centrifugal Filter Devices

Fast and Easy Protein Concentration

Amicon® Ultra Centrifugal Filter devices offer rapid ultrafiltration, efficiently concentrating proteins from both dilute and complex sample matrices. With their vertical design and ample membrane surface area, these devices ensure quick sample processing, high sample recovery, and up to an 80-fold concentration increase.

The devices are offered with nominal molecular weight limits (NMWLs) of 3 kDa, 10 kDa, 30 kDa, 50 kDa, and 100 kDa in four different volumes: 

  • Amicon® Ultra 0.5 mL Centrifugal Filters
  • Amicon® Ultra 2 mL Centrifugal Filters 
  • Amicon® Ultra 4 mL Centrifugal Filters
  • Amicon® Ultra 15 mL Centrifugal Filters

Advantages:

  • High Recovery: Achieve recovery rates of 90-98% using Ultracel® regenerated cellulose membrane with various molecular weight cut-offs.
  • Quick Processing: Vertical membrane design minimizes concentration polarization and membrane fouling, enabling ultra-fast spin times of just 10–15 minutes.
  • Low Non-specific Binding: Heat-sealed membrane reduces downstream extractables, ensuring minimal non-specific binding.
  • Convenient Monitoring: Translucent housing and volume gradations allow easy sample monitoring.
  • Direct Pipetter Access: Access samples directly with a pipetter, eliminating the need for an additional processing step to recover concentrate.
  • Reverse Spin Capability: Consistently achieve maximum protein recoveries, even with small, dilute samples, thanks to the reverse spin capability.
  • Low Sample Loss: Physical deadstop prevents spinning to dryness, minimizing the risk of sample loss.
  • Broad Chemical Compatibility: Compatible with a wide range of aqueous solutions spanning pH 1 to 9.
  • Consistent and Reliable: Enjoy predictable concentration factors without sample drying out, ensuring consistent and reliable sample preparation.
  • Rapid Protein Concentration: Concentrate proteins 25- to 80-fold in a single step, facilitating rapid protein concentration.

Applications:

  • Concentrating biological samples containing antigens, antibodies, enzymes, nucleic acids, or microorganisms.
  • Purifying macromolecular components found in tissue culture extracts or cell lysates and removing proteins before HPLC.
  • Concentrating dilute or pre-purified proteins from column eluents.
  • Performing desalting, buffer exchange, and protein dialysis.
  • Conducting size exclusion and protein fractionation.

Explore the available Amicon® Ultra Centrifugal Filter Devices

Product CodeProduct Name Brand PK
UFC510096Amicon Ultra 0.5ML 100KDaMerck 96/PK
UFC510024Amicon Ultra 0.5ML 100KMerck 24/PK
UFC510008Amicon Ultra 0.5ML 100 KDa 8PKMerck 8/PK
UFC5050BKAmicon Ultra 0.5ML 50KDaMerck 500/PK
UFC505096Amicon Ultra 0.5 ML 50KDaMerck 96/Pk
UFC505024Amicon Ultra 0.5ML 50KMerck 24/PK
UFC505008Amicon Ultra 0.5ML 50KMerck 8/PK
UFC5030BKAmicon Ultra 0.5ML 30KDaMerck500/PK
UFC503096Amicon Ultra 0.5 ML 30 KDaMerck 96/Pk
UFC503024Amicon Ultra 0.5ML 30KMerck 24PK
UFC503008Amicon Ultra 0.5ML 30KDaMerck 8/PK
UFC5010BKAmicon Ultra 0.5ML 10K 500PKMerck 500/PK
UFC501096Amicon Ultra 0.5ML 10KDaMerck 96PK
UFC501024Amicon Ultra 0.5ML 10 KDaMerck 24/PK
UFC501008Amicon Ultra 0.5ML 10KMerck 8PK
UFC5003BKAmicon Ultra 0.5ML 3KMerck500PK
UFC500396Amicon Ultra 0.5ML 3 KDaMerck 96/PK
UFC500324Amicon Ultra 0.5ML 3 KDaMerck 24/PK
UFC500308Amicon Ultra 0.5ML 3 KDaMerck 8/PK
UFC210024Amicon Ultra 2ML 100KMerck 24P
UFC205024PLAmicon Ultra 2ML PRE-LAUNCHMerck 50/PK
UFC205024Amicon Ultra 2ML 50 KDaMerck 24/PK
UFC910096Amicon Ultra 15ML 100KDa 96pkMerck 96/PK
UFC910024Amicon Ultra 15ML 100KDaMerck 24/PK
UFC910008Amicon Ultra 15ML 100KDaMerck 8/PK
UFC905096Amicon Ultra 15ML 50KDaMerck 96/PK
UFC905024Amicon Ultra 15ML 50KDaMerck 24/PK
UFC905008Amicon Ultra 15 ML 50KDaMerck 8/PK
UFC903096Amicon Ultra 15ML 30KDaMerck 96/PK
UFC903024Amicon Ultra 15ML 30KDaMerck 24//Pk
UFC903008Amicon Ultra 15 ML 30 KDaMerck 8/Pk
UFC901096Amicon Ultra 15ML 10 KDa 96pMerck 96/PK
UFC901024Amicon Ultra 15ML 10KDaMerck 24/PK
UFC901012Amicon Ultra 15ML 10KDaMerck 12/PK
UFC901008Amicon Ultra 15 ML 10 KDaMerck 8/Pk
UFC900396Amicon Ultra 15ML 3KDaMerck 96/PK
UFC900324Amicon Ultra 15ML 3KDaMerck 24/PK
UFC900308Amicon Ultra 15ML 3 KDaMerck 8/PK
UFC810096Amicon Ultra 4ML 100KDaMerck 96/PK
UFC805096Amicon Ultra 4ML 50KDaMerck 96/PK
UFC805024Amicon Ultra 4ML 50 KDaMerck 24/Pk
UFC805008Amicon Ultra-4 50KDa NMWLMerck 8/PK
UFC803096Amicon Ultra 4ML 30KDaMerck 96/PK
UFC803024Amicon Ultra 4ML 30KDaMerck 24/Pk
UFC203024PLAmicon Ultra 2ML PRE-LAUNCH 30KMerck 24PK
UFC203024Amicon Ultra 2ML 30 KDaMerck 24/PK
UFC201024PLAmicon Ultra 2ML PRE-LAUNCH 10KMerck 24/PK
UFC201024Amicon Ultra 2ML 10 KDaMerck 24/PK
UFC200324PLAmicon Ultra 2ML PRE-LAUNCH 3KMerck 24PK
UFC200324Amicon Ultra 2ML 3 KDaMerck 24/PK
SAM-UFC901008Amicon Ultra 15MLMerck10K
UFC803008Amicon Ultra 4ML 30KDaMerck 8/PK
UFC800396Amicon Ultra 4ML 3KDaMerck 96/PK
UFC800324Amicon Ultra 4ML 3KDaMerck 24/PK
UFC800308Amicon Ultra 4ML 3KDaMerck 8/PK
UFC5100BKAmicon Ultra 0.5ML 100KDaMerck 500/PK

Get a Quote for Amicon® Ultra Centrifugal Filters

Amicon® Stirred Cells

Ideal choice for large volume concentration needs

Ideal choice for large volume concentration needs

Amicon® Stirred Cells are perfect for separating macrosolutes like DNA, RNA, and proteins in large-volume samples ranging from 50 mL to 400 mL. They’re also great for membrane analysis, allowing users to insert membranes of their choice.

Designed for solutions with up to 10% macrosolute concentration, these stirred cells offer high flow rates, making concentration and salt removal quick and easy. Using pressurized ultrafiltration (pUF), they process large sample volumes rapidly for concentration, diafiltration, and buffer exchange. Gas pressure is directly applied for filtration, retaining solutes above the membrane’s nominal molecular weight cut-off (NMWCO) while allowing water and solutes below the cut-off to pass into the filtrate.

Available in three sizes (50 mL, 200 mL, and 400 mL)

Advantages:

  • Ergonomic Design: Easy to open, close, and assemble.
  • Quick Tubing Connectors: Ensure easy and secure setup.
  • Integrated Safety Features: Includes screw threads and pressure relief valve, eliminating the need for external housing. This ensures easier assembly, disassembly, and clear confirmation of proper setup.
  • Leak-Proof Design: Ensures overall superior integrity.
  • Wide Membrane Disc Selection: Offers a broader range of options.
  • Revised User Guide: Provides clearer instructions for operation and gas source connection.
  • Enhanced Support: Better spare parts and accessory assistance.
  • Secure Stir Bar: Minimizes the risk of membrane damage.
  • Gentle Magnetic Stirring: Minimize concentration polarization and shear denaturation with gentle magnetic stirring.
  • Autoclavable: Ensure sterilization as all stirred cells can be autoclaved.

Applications:

  • Concentrate, diafilter, and exchange buffers for macromolecule solutions including proteins, enzymes, antibodies and viruses

Explore the available Amicon Stirred Cells

Product CodeProduct Name Brand
6028Amicon Stirred Cell Reservoir 800 mLMerck
6003Amicon Stirred Cell Selector ValveMerck
UFSC40001Amicon Stirred Cell 400mLMerck
UFSC2001Amicon Stirred Cell 200mLMerck
UFSC20001Amicon Stirred Cell 200mLMerck
UFSC05001Amicon Stirred Cell 50mLMerck
6015Amicon Stirred Cell ManifoldMerck
UFSC200MTAmicon Stirred Cell 200mL Maintenance kit (stir bar assembly, 2 each seals, tubing kit)Merck
UFSC050SLAmicon Stirred Cell 50mL Seal Kit (3 each o-ring and gasket)Merck

Get a Quote for Amicon® Stirred Cells

Amicon® Pro Purification System

Purify, exchange buffer and concentrate in one device

Simplify and streamline your protein purification process with the all-in-one Amicon® Pro Purification System. This innovative device combines affinity-based spin column purification with downstream sample concentration and buffer exchange, eliminating the need for multiple devices and risky sample transfers.

With a large reservoir that can handle various sample volumes, the Amicon® Pro reduces hands-on time and minimizes centrifugation steps. Simply attach the included Amicon® Ultra Filter for simultaneous elution, concentration, and highly efficient buffer exchange (>99%) in a single spin

Advantages:

  • High Yield: Minimize sample loss with no need for sample transfer.
  • Gentle: Innovative design ensures gentle, continuous flow for efficient buffer exchange.
  • Fast: Achieve purified protein in your preferred buffer in just 5 spins, directly from lysate.
  • Flexible: Easily configure the modular device to accommodate various sample preparation requirements.

Applications:

  • Affinity Purification
  • Depletion of Abundant Proteins
  • Protein Enrichment
  • Buffer Exchange
  • Desalting
  • Clean-up of Antibody Labeling Reactions
Amicon® Pro Purification System performance comparison with other systems

Explore the available Amicon Pro Purification Products

Amicon® Pro Purification Kits 12/pk Includes reagent kit (resin and buffers)Reagent Kit OnlyNMWCO: 3,000NMWCO: 10,000NMWCO: 30,000NMWCO: 50,000NMWCO: 100,000
Amicon® Pro Affinity Concentration Kit Ni-NTAACR5000NTACK5003NTACK5010NTACK5030NTACK5050NTACK5100NT
Amicon® Pro Affinity Concentration Kit Protein AACR5000PAACK5003PAACK5010PAACK5030PAACK5050PAACK5100PA
Amicon® Pro Affinity Concentration Kit Protein GACR5000PGACK5003PGACK5010PGACK5030PGACK5050PGACK5100PG
Amicon® Pro Affinity Concentration Kit GSTACR5000GSACK5003GSACK5010GSACK5030GSACK5050GSACK5100GS
Amicon® Pro purification system — No Reagents IncludedNMWCO: 3,000NMWCO: 10,000NMWCO: 30,000NMWCO: 50,000NMWCO: 100,000
Amicon® Pro Purification System Trial Pack 2/pkACS500302ACS501002ACS503002ACS505002ACS510002
Amicon® Pro Purification System 12/pkACS500312ACS501012ACS503012ACS505012ACS510012
Amicon® Pro Purification System 24/pkACS500324ACS501024ACS503024ACS505024ACS510024
Amicon® Pro Purification System 24/pk without Amicon® Ultra 0.5 mL filter:ACS500024

Get a Quote for Amicon® Pro Purification System

From our knowledge base

Protein Purification with Merck Amicon Ultra Centrifugal Filters Product Guide
2 min read

Protein Purification with Merck Amicon® Ultra Centrifugal Filters

Learn how to choose the right NMWL cut-off, leverage the vertical membrane design for 10-minute spin times, and apply the reverse-spin recovery technique to maximise protein yield — from antibody concentration to buffer exchange.

Protein concentration Buffer exchange Sample prep NMWL selection
Read the guide → Available in Thai & English

Interested in Amicon® ultrafiltration devices for your lab? Our specialists are ready to help you find the right fit — from Ultra centrifugal filters and stirred cells to the Pro purification system for protein concentration, buffer exchange, desalting and purification.

Reach us via our Inquiry Form or LINE. We are happy to help!

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